Chronic liver diseases are an important public health problem, with an incidence in Europe of 5,82% [1]. They have multiple causes, many of which are increasing in prevalence. The final common pathway of chronic liver disease is tissue destruction and attempted regeneration, a pathway that triggers fibrosis and eventual cirrhosis. Assessment of fibrosis is important not only for diagnosis but also for management, prognostic evaluation, and follow-up of patients with chronic liver disease. For years, liver biopsy has been considered the standard reference in the staging of hepatic fibrosis. However, approximately 25% of patients experience pain during the invasive procedure, and 0.3%–0.6% of patients experience severe complications, such as bleeding and even death [2].
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