Breast cancer (BC) is a diverse collection of tumors that range greatly in terms of their molecular makeup, biological behavior, clinical presentation, and therapeutic response when it is categorized according to the disease’s outward symptoms and indicators. Mid-18th century ideas for early surgical excision of the breast tumor before something reached the lymph node nodes resulted from the fact that cancer was a confined illness that developed in phases instead of a de novo systemic disease. Resulting in recommendations for doing an early surgical excision of the breast tumor before it had axillary lymph nodes were affected by the spread. Trastuzumab (Herceptin), the first specific anti-HER2 (human epidermal growth factor 2) medication, a drug used to treat metastatic BC, was approved [1].
Pathological Prognostic Factors and Classification of Breast Cancer
